Services
EnquBio's Comprehensive Drug Discovery Solutions & Services
At EnquBio, our expert team delivers high quality, efficient, and dependable R&D solutions that enable pharmaceutical and biotech partners to advance and expand their drug development pipelines.
- Discovery Biology
- Plate-Based Pharmacology
- Immunology
- Ex Vivo Pharmacology
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In Vivo Pharmacology
- Inflammation & Autoimmune Diseases Models
- Syngeneic and Cell Line-Derived Xenograft (CDX) Models
- Humanized Immuno-Oncology Models
- FLI and BLI based optical in vivo imaging for orthotopic models and drug biodistribution
- Pharmacokinetic and Pharmacodynamic (PK/PD)
- Non-GLP Toxicology
- Other In Vivo Efficacy Models
- Biomarker & Bioanalysis
Discovery Biology
Drive faster drug target validation and development with EnquBio’s Discovery Biology Services. Our specialized team combine genome editing, custom cell line engineering, iPSC model systems, and functional assays to link molecular targets to phenotypic outcomes across a broad range of therapeutic areas. By harnessing cutting-edge platforms and efficient, cost-conscious workflows, we simplify early-stage research, allowing you to prioritize and propel your most promising candidates forward.
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Plate-Based Pharmacology
Streamline your drug discovery efforts with EnquBio’s expert-led Plate-Based Pharmacology services. Our validated and custom assay platforms support high-throughput screening (384- and 1536-well plates), hit-to-lead progression, and lead optimization across diverse therapeutic areas, target classes, and modalities. Backed by cutting-edge instrumentation, efficient workflows, and deep domain expertise, we deliver comprehensive pharmacological profiling to accelerate your therapeutic pipeline.
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Immunology
Our immunology platforms support a broad range of preclinical research needs, with capabilities spanning in vitro immunology assays and immune cell isolation and culturing. These platforms are designed to help clients evaluate immune-modulating compounds, characterize cell-based responses, and explore mechanism of action in a controlled, human-relevant system. With access to banked and fresh human PBMCs, T cells, B cell, NK cells, and myeloid cell populations, we provide flexible and scalable solutions for immuno-oncology, autoimmune, and inflammation studies.
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Ex Vivo Pharmacology
Ex vivo pharmacology uses freshly collected human and animal tissues, as well as blood and primary cells, to study drug activity outside the body. These systems provide a more physiologically relevant context than conventional in vitro assays by preserving key features of the native biological environment, including multicellular interactions, local signaling, and tissue architecture. Studies may involve direct treatment of fresh samples or downstream analysis of samples collected from in vivo studies—supporting deeper evaluation of drug response, mechanism of action, and translational understanding across discovery and development.
At EnquBio, our ex vivo capabilities are built on strong in vitro and in vivo platforms, enabling integrated study designs across fresh tissues, blood, and primary cells—including samples from our own in vivo studies. Our scientists bring more than 10 years of experience supporting global biopharmaceutical companies across drug discovery and development. By combining deep assay-development expertise with advanced analytical technologies, we generate comprehensive, multidimensional datasets that help clients interpret complex biology, strengthen translational confidence, and support stronger decisions across their programs.
In Vivo Pharmacology
At EnquBio, we specialize in guiding model selection and developing customized in vivo systems aligned with your specific research objectives. With extensive experience in preclinical pharmacology, our team delivers industry-leading quality and reproducible data across a wide range of therapeutic areas, positioning us as a trusted and agile partner for your in vivo research programs.
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Biomarker & Bioanalysis
EnquBio provides integrated biomarker and bioanalytical services to support preclinical, translational, and exploratory clinical research. We analyze a broad range of biological samples, including cell lysates, culture supernatants, serum, plasma, PBMCs, whole blood, and tissue-derived samples, to evaluate target engagement, pathway modulation, pharmacodynamic responses, and treatment-related biological changes.
Our core capabilities include soluble protein and cytokine quantification, protein expression and signaling analysis, multicolor flow cytometry, RT-qPCR and ddPCR, supported by platforms including MSD and ProteinSimple Jess.
From established assays to customized, fit-for-purpose methods, our team supports assay execution, data analysis, interpretation, and study reporting to generate reliable, decision-ready data across drug discovery and development programs.