Biomarker Discovery Platforms
EnquBio’s Biomarker Discovery Platform is designed to support data-driven therapeutic development by enabling precise, reliable, and scalable biomarker identification and validation. Our integrated services combine high-dimensional analytics, cutting-edge technologies, and deep immunological expertise to help clients assess target engagement, understand mechanism of action, evaluate pharmacodynamic responses, and stratify patient populations.
We offer a comprehensive suite of validated and customizable assay platforms — including flow cytometry, MSD multiplex cytokine analysis, real-time qPCR, automated western blot (Jess), and clinical sample profiling — tailored to meet the demands of discovery, translational, and preclinical research. Whether you’re seeking mechanistic insights, monitoring immune modulation, or optimizing biomarker strategies for clinical translation, our platform delivers the scientific depth and operational flexibility needed to advance your pipeline with confidence.
Flow Cytometry
Achieve a comprehensive analysis of the immune system by taking advantage of our in-house flow cytometry services. Identification of various cell populations supports a deep interrogation of the immune response elicited from novel therapeutics. Our streamlined process for tissue dissociation, cell isolation, staining and acquisition, and systemic and tumor-infiltrating immune cells allows you to review the data and make time-sensitive decisions regarding compounds and studies.
MSD Cytokine/Chemokine Analysis (Multiplex)
EnquBio leverages the Meso Scale Discovery® (MSD) platform’s plate-based electrochemiluminescence (ECL) technology to provide reliable, accurate data for a variety of bioanalytical assays. In comparison to traditional ELISA techniques, the MSD-ECL assays provide improved sensitivity and dynamic range while maintaining excellent precision and robustness.
Western Blot by Protein Simple JESS (Fully Automatic)
The LI-COR Odyssey Western blot delivers quantitative results for target protein detection using the platform’s infrared technology. This can improve on the sensitivity achieved using traditional chemiluminescent detection systems. EnquBio performs accurate, reproducible, quantitative Western blot assays leveraging this platform.
Real-Time qPCR (High Throughput)
EnquBio offers Real-Time PCR (RT-PCR), Quantitative PCR (qPCR), and Droplet Digital™ PCR (ddPCR™) platforms as part of our extensive technology suite supporting molecular assays. Our molecular laboratories are equipped with the latest generation of PCR equipment including Applied Biosystems QuantStudio 7 Flex or Pro with both 96- and 384-well fast-cycle options and TaqMan Array Cards for qPCR as well as QX200 and QX ONE ddPCR Systems from Bio-Rad.
Clinical Sample Analysis
Translate discovery into impact with EnquBio’s clinical sample analysis services. We integrate advanced analytical workflows with validated biomarker panels to support translational research, patient stratification, and clinical trial sample evaluation. Our end-to-end capabilities—from sample processing to data interpretation—enable actionable insights that bridge bench-to-bedside needs in personalized medicine.